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1. Research Background and Significance Skin and Skin Aging As the largest organ of the human body, the skin performs the critical function of protecting the body from environmental damage. It also plays a vital role in physiological processes such as thermoregulation and sensory perception. The structural integrity of the skin primarily relies on the dynamic extracellular matrix (ECM), which is mainly...

1. Definition and Characteristics of Cold Atmospheric Plasma (CAP) （1）Definition Cold Atmospheric Plasma (CAP) is a partially ionized non-equilibrium plasma that operates at or near room temperature and atmospheric pressure. Unlike traditional plasmas (which require high temperatures and low pressures), its room-temperature operation makes it highly suitable for medical and skincare applications. It is composed of charged particles (electrons, ions), reactive oxygen...

1. Research Background and Objectives Cold Atmospheric Plasma (CAP) is a type of plasma generated at room temperature, with potential antibacterial and anti-tumor properties. Acidic Fibroblast Growth Factor (aFGF) is a long-acting cell proliferation factor that can promote the proliferation of various cells. This study combines these two technologies for the first time to explore their synergistic effect in multi-tissue regeneration. 2....

1. Research Background and Objectives Background CAP is a room-temperature partially ionized gas that generates reactive oxygen and nitrogen species (RONS), ultraviolet radiation, and electric fields. These components allow CAP to regulate cell viability, proliferation, migration, and apoptosis—making it widely applicable in biomedical fields like antimicrobial therapy, wound healing, and cancer treatment. However, the specific mechanisms by which CAP interacts with distinct...

1. Research Background and Objectives Background Diabetic patients often suffer from delayed wound healing due to factors such as hyperglycemia, neuropathy, and impaired immune function. This not only increases the risk of infections but also may lead to severe consequences like amputation. Traditional treatments have limited efficacy in addressing the complex pathological mechanisms of diabetic wounds. Cold atmospheric plasma (CAP) is a...

1. Combination with Vitamin C (1) Principle Cold Atmospheric Plasma (CAP) can promote the metabolism and microcirculation of skin cells, thereby enhancing the skin's absorption capacity. Vitamin C is an antioxidant that functions in skin brightening, antioxidation, and promotion of collagen synthesis. When the two are combined, CAP helps the skin absorb vitamin C more effectively, thereby enhancing the skin-brightening and anti-aging...